Title : Alteration of macrophage responsiveness to platelet-activating factor by interferon-gamma and lipopolysaccharide.

Pub. Date : 1996 Dec 15

PMID : 8954615






4 Functional Relationships(s)
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1 Pretreatment of murine peritoneal macrophages with either LPS or IFN-gamma suppressed macrophage responsiveness to both PAF-induced calcium mobilization and superoxide anion (O2-) production. Superoxides interferon gamma Mus musculus
2 Pretreatment of murine peritoneal macrophages with either LPS or IFN-gamma suppressed macrophage responsiveness to both PAF-induced calcium mobilization and superoxide anion (O2-) production. Superoxides interferon gamma Mus musculus
3 LPS and IFN-gamma treatment also decreased PAF-induced, calcium-dependent O2- production. Superoxides interferon gamma Mus musculus
4 When added together, IFN-gamma increased the suppression of PAF-induced intracellular calcium mobilization and inhibited O2- production mediated by LPS. Superoxides interferon gamma Mus musculus