Pub. Date : 1996 Dec
PMID : 8952699
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Characterization of a novel amphiregulin-related molecule in 12-O-tetradecanoylphorbol-13-acetate-treated breast cancer cells. | Tetradecanoylphorbol Acetate | amphiregulin | Homo sapiens |
| 2 | Amphiregulin (AR) can be induced at the mRNA level by 17-beta-estradiol (E2) or the phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). | Tetradecanoylphorbol Acetate | amphiregulin | Homo sapiens |
| 3 | Amphiregulin (AR) can be induced at the mRNA level by 17-beta-estradiol (E2) or the phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). | Tetradecanoylphorbol Acetate | amphiregulin | Homo sapiens |
| 4 | Amphiregulin (AR) can be induced at the mRNA level by 17-beta-estradiol (E2) or the phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). | Tetradecanoylphorbol Acetate | amphiregulin | Homo sapiens |
| 5 | Amphiregulin (AR) can be induced at the mRNA level by 17-beta-estradiol (E2) or the phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). | Tetradecanoylphorbol Acetate | amphiregulin | Homo sapiens |
| 6 | This study compares the effects of TPA and E2 on the regulation of processing of AR isoforms and on subcellular localization in human MCF-7 breast cancer cells. | Tetradecanoylphorbol Acetate | amphiregulin | Homo sapiens |
| 7 | AR isoforms of 28, 18, and 10 kDa and an additional species of approximately 55-60 kDa were detected in the cellular conditioned media after TPA stimulation. | Tetradecanoylphorbol Acetate | amphiregulin | Homo sapiens |
| 8 | These data suggest that TPA activation of PKC may be involved in post-translational modifications of AR, such as glycosylation, and in alteration of its subcellular routing to predominantly a secretory pathway. | Tetradecanoylphorbol Acetate | amphiregulin | Homo sapiens |