Pub. Date : 1996
PMID : 8941167
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sertindole and risperidone demonstrate polymorphic metabolism characteristics mirroring the CYP 2D6 phenotype. | sertindole | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 2 | The inhibitory potentials of sertindole at CYP 2D6 and CYP 3A are modest and not likely to be of clinical significance. | sertindole | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 3 | However, in those patients taking CYP 2D6 inhibitors or in those who are genotypic poor metabolizers, concentrations achieved by sertindole and its metabolites might result in moderate inhibition of CYP 3A. | sertindole | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |