Pub. Date : 1996 Oct
PMID : 8922193
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: Inhibition of Pgp can affect the distribution and the pharmacokinetics of anthracyclines, causing marked changes in their toxicity. | Anthracyclines | phosphoglycolate phosphatase | Mus musculus |
| 2 | Since both paclitaxel and cremophor are substrates of Pgp, it was hypothesized that they could modify the pharmacokinetics of anthracyclines in a similar fashion. | Anthracyclines | phosphoglycolate phosphatase | Mus musculus |