Pub. Date : 1996 Oct 28
PMID : 8921979
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Benzo[a]pyrenediol-epoxide induces loss of heterozygosity in Chinese hamster ovary cells heterozygous at the aprt locus. | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | adenine phosphoribosyltransferase | Cricetulus griseus |
| 2 | The analysis of mutation in the aprt heterozygote was done to investigate the frequency of loss of heterozygosity (LOH) events following BPDE treatment. | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | adenine phosphoribosyltransferase | Cricetulus griseus |
| 3 | Using PCR to produce an artificial restriction fragment length polymorphism in the functional aprt allele, BPDE was found to induce LOH in about one-quarter of the mutants recovered. | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | adenine phosphoribosyltransferase | Cricetulus griseus |