Title : Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.

Pub. Date : 1996 Nov 12

PMID : 8916907






1 Functional Relationships(s)
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1 Further, the reduced GTPase reaction rate that characterizes the oncogenic effect of many of the p21 mutants found in human tumors seems to be a consequence of a slightly reduced pKa of the gamma-phosphate group of bound GTP. Guanosine Triphosphate H3 histone pseudogene 16 Homo sapiens