Title : Role of dehydroascorbate in rabbit erythrocyte hexokinase inactivation induced by ascorbic acid/Fe(II).

Pub. Date : 1996 Oct 15

PMID : 8900411






3 Functional Relationships(s)
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1 Role of dehydroascorbate in rabbit erythrocyte hexokinase inactivation induced by ascorbic acid/Fe(II). Dehydroascorbic Acid hexokinase-2 Oryctolagus cuniculus
2 The H202 formed during this process accelerates the formation of dehydroascorbic acid, which appears to be necessary and sufficient to induce hexokinase inactivation. Dehydroascorbic Acid hexokinase-2 Oryctolagus cuniculus
3 Taken together, these results demonstrate that the process of hexokinase inactivation induced by ascorbic acid/Fe(II) is mediated by dehydroascorbate and that iron and H202 have the sole function of accelerating its formation. Dehydroascorbic Acid hexokinase-2 Oryctolagus cuniculus