Title : Chemosensitivity of head and neck squamous carcinoma cell lines is not primarily correlated with glutathione level but is modified by glutathione depletion.

Pub. Date : 1996

PMID : 8898974






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 On the basis of this interaction with both endogenous and synthetic substances, glutathione and the key enzyme for its conjugation, glutathione S-transferase, appear to be critical determinants in tumor cell resistance to several antineoplastic drugs, e.g. platinum analogs. Platinum glutathione S-transferase kappa 1 Homo sapiens