Title : Rgt1p of Saccharomyces cerevisiae, a key regulator of glucose-induced genes, is both an activator and a repressor of transcription.

Pub. Date : 1996 Nov

PMID : 8887670






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Glucose alters Rgt1p function through a pathway that includes two glucose sensors, Snf3p and Rgt2p, and Grr1p. Glucose SCF ubiquitin ligase complex subunit GRR1 Saccharomyces cerevisiae S288C
2 Grr1p, a component of the glucose signaling pathway, is required both for inactivation of Rgt1p repressor function by low levels of glucose and for conversion of Rgt1p into an activator at high levels of glucose. Glucose SCF ubiquitin ligase complex subunit GRR1 Saccharomyces cerevisiae S288C
3 Grr1p, a component of the glucose signaling pathway, is required both for inactivation of Rgt1p repressor function by low levels of glucose and for conversion of Rgt1p into an activator at high levels of glucose. Glucose SCF ubiquitin ligase complex subunit GRR1 Saccharomyces cerevisiae S288C
4 Grr1p, a component of the glucose signaling pathway, is required both for inactivation of Rgt1p repressor function by low levels of glucose and for conversion of Rgt1p into an activator at high levels of glucose. Glucose SCF ubiquitin ligase complex subunit GRR1 Saccharomyces cerevisiae S288C
5 Thus, signals generated by two different glucose sensors act through Grr1p to determine Rgt1p function. Glucose SCF ubiquitin ligase complex subunit GRR1 Saccharomyces cerevisiae S288C