Title : Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.

Pub. Date : 1996 Sep

PMID : 8886603






1 Functional Relationships(s)
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1 In contrast, orphenadrine, an inhibitor of CYP2B forms, produced a 51 +/- 4% decrease in S-mephenytoin N-demethylase activity in human liver microsomes and a 45% decrease in recombinant microsomes expressing CYP2B6. Orphenadrine cytochrome P450 family 2 subfamily B member 6 Homo sapiens