Title : Mechanism of signaling by growth hormone receptor.

Pub. Date : 1996 Oct

PMID : 8874495






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Tyrosyl phosphorylation of GH receptor and JAK2 recruits and activates signaling molecules such as Stat transcription factors, SHC, and insulin receptor substrates 1 and 2 that lead to the release of second messengers such as diacylglycerol, calcium, and nitric oxide and the activation of enzymes such as mitogen-activated protein kinase, protein kinase C, phospholipase A2, and phosphatidylinositol 3"-kinase. Calcium growth hormone receptor Homo sapiens