Title : The catalytic activity of the endoplasmic reticulum-resident protein microsomal epoxide hydrolase towards carcinogens is retained on inversion of its membrane topology.

Pub. Date : 1996 Oct 1

PMID : 8870659






1 Functional Relationships(s)
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1 Diol epoxides formed by the sequential action of cytochrome P-450 and the microsomal epoxide hydrolase (mEH) in the endoplasmic reticulum (ER) represent an important class of ultimate carcinogenic metabolites of polycyclic aromatic hydrocarbons. Polycyclic Aromatic Hydrocarbons epoxide hydrolase 1, microsomal Mus musculus