Title : Mechanism and structure based inhibitors of phospholipase C enzymes.

Pub. Date : 1996

PMID : 8869740






2 Functional Relationships(s)
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1 The solution conformations of the lipophilic phospholipid analogs, (diheptanoylphosphatidyl(2-O-methyl)inositol for PI-PLC and a dihexanoyl-sn-(3-N-benzylaminoglycero)phosphoramidocholine for PC-PLC, have been determined using NMR methodology and the interaction of these compounds with bacterial enzymes has been examined. Phospholipids heparan sulfate proteoglycan 2 Homo sapiens
2 The solution conformations of the lipophilic phospholipid analogs, (diheptanoylphosphatidyl(2-O-methyl)inositol for PI-PLC and a dihexanoyl-sn-(3-N-benzylaminoglycero)phosphoramidocholine for PC-PLC, have been determined using NMR methodology and the interaction of these compounds with bacterial enzymes has been examined. Phospholipids heparan sulfate proteoglycan 2 Homo sapiens