Pub. Date : 1996 Feb
PMID : 8868260
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Corticosterone controls interleukin-1 beta expression and sickness behavior in the rat. | Corticosterone | interleukin 1 beta | Rattus norvegicus |
| 2 | Administration of corticosterone 1 h before LPS lowered the splenic IL-1 beta mRNA content compared to LPS-treated adrenal-intact rats that did not receive corticosterone and inhibited fever and anorexia, whereas the glucocorticoid did not attenuate the endotoxin-induced suppression of locomotor activity. | Corticosterone | interleukin 1 beta | Rattus norvegicus |
| 3 | Our data suggest that during inflammatory conditions body temperature, sickness behavior and the synthesis of IL-1 beta are controlled by corticosterone. | Corticosterone | interleukin 1 beta | Rattus norvegicus |