Title : Suppression of two cloned smooth muscle-derived delayed rectifier potassium channels by cholinergic agonists and phorbol esters.

Pub. Date : 1995 Dec

PMID : 8848000






3 Functional Relationships(s)
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1 In oocytes coexpressing hm3 receptors and Kv channels, acetylcholine (ACh, 100 microM) decreased the whole-oocyte Kv channel current (IKv) by 72% over 20 min. Acetylcholine cholinergic receptor muscarinic 3 Homo sapiens
2 In oocytes coexpressing hm3 receptors and Kv channels, acetylcholine (ACh, 100 microM) decreased the whole-oocyte Kv channel current (IKv) by 72% over 20 min. Acetylcholine cholinergic receptor muscarinic 3 Homo sapiens
3 In oocytes expressing only Kv channels phorbol esters (phorboldibutyrate) and phorbol dideconoate (10-30 nM) mimicked the action of ACh on IKv in oocytes coexpressing hm3 receptors. Acetylcholine cholinergic receptor muscarinic 3 Homo sapiens