Title : Hypolipidemic activity of select fibrates correlates to changes in hepatic apolipoprotein C-III expression: a potential physiologic basis for their mode of action.

Pub. Date : 1995 Dec

PMID : 8847480






4 Functional Relationships(s)
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1 In the current studies, we sought to determine whether the selected fibrates, bezafibrate, clofibrate, fenofibrate, and gemfibrozil, could reduce hepatic apoC-III mRNA and plasma apoC-III levels. Gemfibrozil apolipoprotein C3 Homo sapiens
2 In the current studies, we sought to determine whether the selected fibrates, bezafibrate, clofibrate, fenofibrate, and gemfibrozil, could reduce hepatic apoC-III mRNA and plasma apoC-III levels. Gemfibrozil apolipoprotein C3 Homo sapiens
3 Gemfibrozil strongly reduced plasma triglyceride levels and had an intermediate but significant effect on apoC-III mRNA and plasma apoC-III levels. Gemfibrozil apolipoprotein C3 Homo sapiens
4 Gemfibrozil strongly reduced plasma triglyceride levels and had an intermediate but significant effect on apoC-III mRNA and plasma apoC-III levels. Gemfibrozil apolipoprotein C3 Homo sapiens