Title : The role of ascorbic acid and xylitol in etomidate-induced adrenocortical suppression in humans.

Pub. Date : 1996 Jul

PMID : 8842654






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1 Since the generation of steroids requires reductive and energy rich equivalents, the present study examined whether supplementation with ascorbic acid or xylitol, a major source of NADPH, could attenuate adrenal suppression by etomidate in human subjects by promoting the turnover rate of 11-beta-hydroxylase. Xylitol 2,4-dienoyl-CoA reductase 1 Homo sapiens