Title : DNA damage and p53 induction do not cause ZD1694-induced cell cycle arrest in human colon carcinoma cells.

Pub. Date : 1996 Oct 15

PMID : 8840989






1 Functional Relationships(s)
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1 With a single exposure at a concentration of 1 microM for 2 h, ZD1694 completely inhibits thymidylate synthase over 72 h and causes a sustained growth for at least 120 h, DNA damage, and p53 induction in human carcinoma cells. raltitrexed tumor protein p53 Homo sapiens