Pub. Date : 1996 Mar
PMID : 8839044
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Human cytochrome P450 1A1 (1A1) and microsomal epoxide hydrolase (mEH)-dependent metabolic activation of benzo[a]pyrene (BP) have been reconstituted with microsomes from yeast cells expressing the two enzymes. | Benzo(a)pyrene | epoxide hydrolase 1, microsomal | Mus musculus |
2 | Human cytochrome P450 1A1 (1A1) and microsomal epoxide hydrolase (mEH)-dependent metabolic activation of benzo[a]pyrene (BP) have been reconstituted with microsomes from yeast cells expressing the two enzymes. | Benzo(a)pyrene | epoxide hydrolase 1, microsomal | Mus musculus |
3 | A minimum kinetic model of BP metabolism by 1A1 and mEH was constructed on the basis of the overall kinetic parameters (Vmax, Km) for a number of individual steps determined with human 1A1 and mEH expressed in yeast. | Benzo(a)pyrene | epoxide hydrolase 1, microsomal | Mus musculus |
4 | A minimum kinetic model of BP metabolism by 1A1 and mEH was constructed on the basis of the overall kinetic parameters (Vmax, Km) for a number of individual steps determined with human 1A1 and mEH expressed in yeast. | Benzo(a)pyrene | epoxide hydrolase 1, microsomal | Mus musculus |