Title : Modification of sarcoplasmic reticulum gene expression in pressure overload cardiac hypertrophy by etomoxir.

Pub. Date : 1996 Sep

PMID : 8836044






2 Functional Relationships(s)
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1 The reduction in steady-state mRNA levels for SR phospholamban (PLP) and Ca2+ release channel (CRC) in the pressure-overloaded animals was also prevented without any reduction in the extent of cardiac hypertrophy by treatment with etomoxir. etomoxir proteolipid protein 1 Rattus norvegicus
2 Similar beneficial effects of etomoxir treatment were also evident when the gene expression for SR SERCA2, PLP, and CRC in the hypertrophied heart was normalized with respect to mRNA for GAPDH. etomoxir proteolipid protein 1 Rattus norvegicus