Title : Suppression of splenic natural killer cell activity in a mouse model for binge drinking. II. Role of the neuroendocrine system.

Pub. Date : 1996 Sep

PMID : 8819520






3 Functional Relationships(s)
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1 Other agents were less effective, which suggested a possible role for the diazepam-insensitive GABA-A sites that are recognized by Ro15-4513. Diazepam gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1 Mus musculus
2 The failure of diazepam to suppress NK activity also suggests that increased chloride flux through diazepam-sensitive GABA-A receptors (which is caused by EtOH as well as diazepam) does not mediate NK suppression in this model. Diazepam gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1 Mus musculus
3 The failure of diazepam to suppress NK activity also suggests that increased chloride flux through diazepam-sensitive GABA-A receptors (which is caused by EtOH as well as diazepam) does not mediate NK suppression in this model. Diazepam gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1 Mus musculus