Pub. Date : 1996 Jun
PMID : 8809635
2 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | The stereoselective inhibition of inducible cyclooxygenase (COX-2) by chiral nonsteroidal antiinflammatory drugs (NSAIDs)--ketoprofen, flurbiprofen, and ketorolac--has been investigated. | Ketoprofen | mitochondrially encoded cytochrome c oxidase II | Homo sapiens | ||
| 2 | In the whole blood model, both isoenzymes were inhibited by S-enantiomers with equal potency but S-ketoprofen was the most active on COX-2 (IC50 = 0.024 mumol/L). | Ketoprofen | mitochondrially encoded cytochrome c oxidase II | Homo sapiens | ||