Pub. Date : 1996 Sep 19
PMID : 8808702
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | WAF1/CIP1 increases the susceptibility of p53 non-functional malignant glioma cells to cisplatin-induced apoptosis. | Cisplatin | tumor protein p53 | Homo sapiens |
| 2 | In this study, we show that WAF1/CIP1 was induced in p53-dependent apoptosis of U87-MG glioma cells by cis-diamminedichloroplatinum (cisplatin), and overexpression of WAF1/CIP1 induced apoptosis in U87-MG cells without cisplatin treatment. | Cisplatin | tumor protein p53 | Homo sapiens |
| 3 | In this study, we show that WAF1/CIP1 was induced in p53-dependent apoptosis of U87-MG glioma cells by cis-diamminedichloroplatinum (cisplatin), and overexpression of WAF1/CIP1 induced apoptosis in U87-MG cells without cisplatin treatment. | Cisplatin | tumor protein p53 | Homo sapiens |
| 4 | In this study, we show that WAF1/CIP1 was induced in p53-dependent apoptosis of U87-MG glioma cells by cis-diamminedichloroplatinum (cisplatin), and overexpression of WAF1/CIP1 induced apoptosis in U87-MG cells without cisplatin treatment. | Cisplatin | tumor protein p53 | Homo sapiens |
| 5 | In contrast, the p53-independent apoptosis of GB-1 glioma cells by cisplatin did not express WAF1/CIP1. | Cisplatin | tumor protein p53 | Homo sapiens |