Title : Elimination of potential sites of glycosylation fails to abrogate complement regulatory function of cell surface CD59.

Pub. Date : 1996 Sep 27

PMID : 8798614






2 Functional Relationships(s)
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1 In this study, we specifically examined how deletion or transposition of the site of N-linked glycosylation in the CD59 polypeptide affects its MAC inhibitory function. Nitrogen CD59 molecule (CD59 blood group) Homo sapiens
2 Furthermore, we show that CD59 retains normal MAC regulatory function when mutated to eliminate all potential sites for N-linked glycosylation. Nitrogen CD59 molecule (CD59 blood group) Homo sapiens