Title : Phosphatidylinositol 4,5-bisphosphate provides an alternative to guanine nucleotide exchange factors by stimulating the dissociation of GDP from Cdc42Hs.

Pub. Date : 1996 Sep 27

PMID : 8798610






1 Functional Relationships(s)
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1 We have shown previously that the dbl oncogene product, which represents a prototype for a family of growth regulatory proteins, activates Rho subfamily GTP-binding proteins by catalyzing the dissociation of GDP from their nucleotide binding site. Guanosine Diphosphate MCF.2 cell line derived transforming sequence Homo sapiens