Pub. Date : 1996 Sep
PMID : 8794888
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CsA and FK506 associate with intracellular binding proteins (i.e., CsA with cyclophilin A and FK506 with FKBP12) to form protein/drug complexes that suppress the immune system by preventing activation of T cells in response to antigen presentation. | Tacrolimus | FKBP prolyl isomerase 1A pseudogene 2 | Homo sapiens |
| 2 | CsA and FK506 associate with intracellular binding proteins (i.e., CsA with cyclophilin A and FK506 with FKBP12) to form protein/drug complexes that suppress the immune system by preventing activation of T cells in response to antigen presentation. | Tacrolimus | FKBP prolyl isomerase 1A pseudogene 2 | Homo sapiens |
| 3 | In previous studies, we identified calcineurin mutations that block binding by the cyclophilin A/CsA or FKBP12/FK506 complexes and thereby render yeast cells resistant to the antifungal effects of CsA or FK506. | Tacrolimus | FKBP prolyl isomerase 1A pseudogene 2 | Homo sapiens |
| 4 | In previous studies, we identified calcineurin mutations that block binding by the cyclophilin A/CsA or FKBP12/FK506 complexes and thereby render yeast cells resistant to the antifungal effects of CsA or FK506. | Tacrolimus | FKBP prolyl isomerase 1A pseudogene 2 | Homo sapiens |