Pub. Date : 1996 Sep
PMID : 8794881
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The sphingolipids sphingosine-1-phosphate (SPP) and sphingosylphosphocholine (SPC) stimulate mitogenesis in Swiss 3T3 fibroblasts and stimulate DNA binding activity of activator protein-1 (AP-1). | Sphingolipids | JunB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 2 | The sphingolipids sphingosine-1-phosphate (SPP) and sphingosylphosphocholine (SPC) stimulate mitogenesis in Swiss 3T3 fibroblasts and stimulate DNA binding activity of activator protein-1 (AP-1). | Sphingolipids | JunB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 3 | Thus, critical sphingolipid structural components for AP-1 activation and mitogenic stimulation include the free 2-amino group, the free 3-hydroxyl group, the 4,5-trans double bond, and terminal phosphorylation. | Sphingolipids | JunB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |