Pub. Date : 1996 Jun
PMID : 8764317
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PGE2 reverses AVP inhibition of HCO3- absorption in rat MTAL by activation of protein kinase C. In the medullary thick ascending limb (MTAL) of the rat, prostaglandin E2 (PGE2) reverses inhibition of HCO3- absorption (JHCO3) by arginine vasopressin (AVP) by inhibiting AVP-stimulated adenosine 3",5"-cyclic monophosphate (cAMP) production. | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 2 | PGE2 reverses AVP inhibition of HCO3- absorption in rat MTAL by activation of protein kinase C. In the medullary thick ascending limb (MTAL) of the rat, prostaglandin E2 (PGE2) reverses inhibition of HCO3- absorption (JHCO3) by arginine vasopressin (AVP) by inhibiting AVP-stimulated adenosine 3",5"-cyclic monophosphate (cAMP) production. | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 3 | PGE2 reverses AVP inhibition of HCO3- absorption in rat MTAL by activation of protein kinase C. In the medullary thick ascending limb (MTAL) of the rat, prostaglandin E2 (PGE2) reverses inhibition of HCO3- absorption (JHCO3) by arginine vasopressin (AVP) by inhibiting AVP-stimulated adenosine 3",5"-cyclic monophosphate (cAMP) production. | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 4 | PGE2 reverses AVP inhibition of HCO3- absorption in rat MTAL by activation of protein kinase C. In the medullary thick ascending limb (MTAL) of the rat, prostaglandin E2 (PGE2) reverses inhibition of HCO3- absorption (JHCO3) by arginine vasopressin (AVP) by inhibiting AVP-stimulated adenosine 3",5"-cyclic monophosphate (cAMP) production. | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 5 | PGE2 reverses AVP inhibition of HCO3- absorption in rat MTAL by activation of protein kinase C. In the medullary thick ascending limb (MTAL) of the rat, prostaglandin E2 (PGE2) reverses inhibition of HCO3- absorption (JHCO3) by arginine vasopressin (AVP) by inhibiting AVP-stimulated adenosine 3",5"-cyclic monophosphate (cAMP) production. | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 6 | PGE2 reverses AVP inhibition of HCO3- absorption in rat MTAL by activation of protein kinase C. In the medullary thick ascending limb (MTAL) of the rat, prostaglandin E2 (PGE2) reverses inhibition of HCO3- absorption (JHCO3) by arginine vasopressin (AVP) by inhibiting AVP-stimulated adenosine 3",5"-cyclic monophosphate (cAMP) production. | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 7 | PGE2 reverses AVP inhibition of HCO3- absorption in rat MTAL by activation of protein kinase C. In the medullary thick ascending limb (MTAL) of the rat, prostaglandin E2 (PGE2) reverses inhibition of HCO3- absorption (JHCO3) by arginine vasopressin (AVP) by inhibiting AVP-stimulated adenosine 3",5"-cyclic monophosphate (cAMP) production. | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 8 | PGE2 reverses AVP inhibition of HCO3- absorption in rat MTAL by activation of protein kinase C. In the medullary thick ascending limb (MTAL) of the rat, prostaglandin E2 (PGE2) reverses inhibition of HCO3- absorption (JHCO3) by arginine vasopressin (AVP) by inhibiting AVP-stimulated adenosine 3",5"-cyclic monophosphate (cAMP) production. | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 9 | We conclude that 1) PGE2 reverses AVP inhibition of HCO3- absorption by activation of PKC, 2) PKC likely increases JHCO3 by inhibiting AVP-stimulated cAMP production via a Gi-dependent mechanism, and 3) PKC activity has no influence on basal HCO3- absorption rate. | Dinoprostone | arginine vasopressin | Rattus norvegicus |
| 10 | We conclude that 1) PGE2 reverses AVP inhibition of HCO3- absorption by activation of PKC, 2) PKC likely increases JHCO3 by inhibiting AVP-stimulated cAMP production via a Gi-dependent mechanism, and 3) PKC activity has no influence on basal HCO3- absorption rate. | Dinoprostone | arginine vasopressin | Rattus norvegicus |