Title : Role of oxidative damage and IL-1 beta-converting enzyme-like proteases in Fas-based cytotoxicity exerted by effector T cells.

Pub. Date : 1996 Jul

PMID : 8757963






2 Functional Relationships(s)
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1 On the other hand, the IL-1beta-converting enzyme (ICE)-like protease tetrapeptide inhibitor Ac-YVAD-cmk partially inhibited Fas-based cytotoxicity, while the specific inhibitor of CPP32/Yama Ac-DEVD-CHO was a much more effective inhibitor of Fas-induced apoptosis. N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone caspase 1 Homo sapiens
2 On the other hand, the IL-1beta-converting enzyme (ICE)-like protease tetrapeptide inhibitor Ac-YVAD-cmk partially inhibited Fas-based cytotoxicity, while the specific inhibitor of CPP32/Yama Ac-DEVD-CHO was a much more effective inhibitor of Fas-induced apoptosis. N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone caspase 1 Homo sapiens