Title : Structural characterization of the 1:1 adduct formed between the antitumor antibiotic hedamycin and the oligonucleotide duplex d(CACGTG)2 by 2D NMR spectroscopy.

Pub. Date : 1996 Jul 23

PMID : 8755709






1 Functional Relationships(s)
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1 Furthermore, it is proposed that the 5"-CGT sequence selectivity of hedamycin arises, in part, from complementarity in shape between the chromophore substituents and the major and minor groove at the binding site. hedamycin UDP glycosyltransferase 8 Homo sapiens