Title : Pho85p, a cyclin-dependent protein kinase, and the Snf1p protein kinase act antagonistically to control glycogen accumulation in Saccharomyces cerevisiae.

Pub. Date : 1996 Aug

PMID : 8754836






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Pho85p, a cyclin-dependent protein kinase, and the Snf1p protein kinase act antagonistically to control glycogen accumulation in Saccharomyces cerevisiae. Glycogen cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C
2 In a screen for second site suppressors of the glycogen storage defect of snf1 cells, we identified a mutant gene that restored glycogen accumulation and which was allelic with PHO85, which encodes a member of the cyclin-dependent kinase family. Glycogen cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C
3 In a screen for second site suppressors of the glycogen storage defect of snf1 cells, we identified a mutant gene that restored glycogen accumulation and which was allelic with PHO85, which encodes a member of the cyclin-dependent kinase family. Glycogen cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C
4 In cells with disrupted PHO85 genes, we observed hyperaccumulation of glycogen, activation of glycogen synthase, and impaired glycogen synthase kinase activity. Glycogen cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C