Pub. Date : 1996 Mar
PMID : 8721461
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Heparin-coated circuits reduce the formation of TNF alpha during cardiopulmonary bypass. | Heparin | tumor necrosis factor | Homo sapiens |
2 | Although previous studies have shown that heparin coating of the extracorporeal circuits reduces complement and granulocyte activation, and the inflammatory response, the possible effect of heparin coating on TNF alpha formation and the inflammatory response has not been fully investigated. | Heparin | tumor necrosis factor | Homo sapiens |
3 | CONCLUSION: From these observations, we conclude that heparin coating of the extracorporeal circuits reduces the TNF alpha formation during CPB, which may reduce neutrophil activation. | Heparin | tumor necrosis factor | Homo sapiens |