Title : Catalytic activity of complex I in cell lines that possess replacement mutations in the ND genes in Leber's hereditary optic neuropathy.

Pub. Date : 1996 Jul 1

PMID : 8706709






1 Functional Relationships(s)
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1 An increased ubiquinone-10 content in the mitochondrial membrane of all the mutants, and enhanced succinate dehydrogenase and citrate synthase activities in the ND4 mutant, are proposed to be compensatory changes. Succinic Acid mitochondrially encoded NADH dehydrogenase 4 Homo sapiens