Title : cDNA cloning and expression of a new form of human aryl sulfotransferase.

Pub. Date : 1996 May

PMID : 8697101






3 Functional Relationships(s)
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1 On expression of these cDNAs in COS cells the encoded proteins were capable of sulfonating p-nitrophenol with markedly different affinities: the K(m)s for HAST4 and HAST4v being 73.7 and 7.75 microM, respectively. 4-nitrophenol sulfotransferase family 1A member 2 Homo sapiens
2 On expression of these cDNAs in COS cells the encoded proteins were capable of sulfonating p-nitrophenol with markedly different affinities: the K(m)s for HAST4 and HAST4v being 73.7 and 7.75 microM, respectively. 4-nitrophenol sulfotransferase family 1A member 2 Homo sapiens
3 In addition to having markedly different K(m)s for p-nitrophenol as a substrate, the expressed HAST4/4 proteins also differed significantly in their affinity for the cofactor 3"-phosphoadenosine-5"-phosphosulfate. 4-nitrophenol sulfotransferase family 1A member 2 Homo sapiens