Pub. Date : 1996 Aug
PMID : 8696947
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Heparin-induced overexpression of basic fibroblast growth factor, basic fibroblast growth factor receptor, and cell-associated proteoheparan sulfate in cultured coronary smooth muscle cells. | Heparin | fibroblast growth factor 2 | Bos taurus |
2 | Heparin-induced overexpression of basic fibroblast growth factor, basic fibroblast growth factor receptor, and cell-associated proteoheparan sulfate in cultured coronary smooth muscle cells. | Heparin | fibroblast growth factor 2 | Bos taurus |
3 | Heparin in nanogram quantities may promote or even be required for binding of bFGF to its cognate receptor. | Heparin | fibroblast growth factor 2 | Bos taurus |
4 | The heparin-induced increase in cellular protein content includes a 60% to 100% increase in the expression of pericellular bFGF, FGF-R1, and cell membrane-integrated HSPG. | Heparin | fibroblast growth factor 2 | Bos taurus |
5 | These results indicate that heparin, despite its anti-proliferative potency, stimulates the expression of all components of the bFGF system even in coronary SMCs in which growth is inhibited. | Heparin | fibroblast growth factor 2 | Bos taurus |