Title : FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.

Pub. Date : 1996 Jun 14

PMID : 8681377






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 FLICE binds to the death effector domain of FADD and upon overexpression induces apoptosis that is blocked by the ICE family inhibitors, CrmA and z-VAD-fmk. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone Fas associated via death domain Homo sapiens