Pub. Date : 1996 Jun 28
PMID : 8674115
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This exonuclease activity is intrinsic to the wild-type p53 protein: it copurified with p53 during p53 preparation; only purified wild-type p53, but not identically purified mutant p53 proteins displayed exonuclease activity; the exonuclease activity could be reconstituted from SDS gel-purified and urea-renatured p53 protein and mapped to the core domain of the p53 molecule; and finally, purified p53 protein could be UV-cross-linked to GMP. | guanosine 5'-monophosphorothioate | tumor protein p53 | Homo sapiens |