Title : Ricin depresses cardiac function in the rabbit heart.

Pub. Date : 1996 May

PMID : 8658515






2 Functional Relationships(s)
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1 Compared to the control group, ricin pretreatment markedly decreased ventricular compliance (p < 0.01), diminished maximum left ventricular developed pressure (p < 0.05), and reduced maximal +dp/dt (p < 0.05). dp ricin Ricinus communis
2 thus, ricin reduced both systolic (LVDP and +dp/dt) and diastolic (compliance) left ventricular functions, perhaps due to increased vascular permeability, without altering responses to the alpha- and beta-adrenoceptor agonists phenylephrine and isoproterenol. dp ricin Ricinus communis