Title : Localization of 17beta-hydroxysteroid dehydrogenase and characterization of testosterone in the brain of the male frog.

Pub. Date : 1996 Feb 20

PMID : 8643647






3 Functional Relationships(s)
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1 In the present study, we have investigated the distribution and bioactivity of 17beta-hydroxysteroid dehydrogenase (17beta-HSD) (EC 1.1.1.62; a key enzyme that is required for the formation of testosterone and estradiol) in the brain of the male frog Rana ridibunda. Testosterone hydroxysteroid 17-beta dehydrogenase 7 Homo sapiens
2 In the present study, we have investigated the distribution and bioactivity of 17beta-hydroxysteroid dehydrogenase (17beta-HSD) (EC 1.1.1.62; a key enzyme that is required for the formation of testosterone and estradiol) in the brain of the male frog Rana ridibunda. Testosterone hydroxysteroid 17-beta dehydrogenase 7 Homo sapiens
3 These data indicate that 17beta-HSD is expressed in a subpopulation of gliocytes in the frog telencephalon and that telencephalic cells are capable of synthesizing various androgens, including dehydroepiandrosterone, androstenedione, testosterone, and 5alpha-dihydrotestosterone. Testosterone hydroxysteroid 17-beta dehydrogenase 7 Homo sapiens