Title : Human endometrial fibroblasts immortalized by simian virus 40 large T antigen differentiate in response to a decidualization stimulus.

Pub. Date : 1996 Jun

PMID : 8641169






2 Functional Relationships(s)
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1 Biochemical differentiation of this cell line has been demonstrated by the ability of a decidualizing stimulus, 8-bromo-cAMP plus medroxyprogesterone acetate (MPA), to induce PRL secretion and increase the enzymatic activity of estrone sulfatase. 8-Bromo Cyclic Adenosine Monophosphate prolactin Homo sapiens
2 MPA, alone or in combination with estradiol, was unable to elicit this response, but potentiated the effect of 8-bromo-cAMP on PRL production and estrone sulfatase activity. 8-Bromo Cyclic Adenosine Monophosphate prolactin Homo sapiens