Title : Controlled modification of acidity in cholecystokinin B receptor antagonists: N-(1,4-benzodiazepin-3-yl)-N'-[3-(tetrazol-5-ylamino) phenyl]ureas.

Pub. Date : 1996 Feb 16

PMID : 8632408






1 Functional Relationships(s)
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1 The design, synthesis, and biological activity of a novel series of CCK-B receptor antagonists (1) which incorporate a tetrazol-5-ylamino functionality attached to the phenyl ring of the arylurea moiety of L-365,260 are described. l-365 cholecystokinin B receptor Rattus norvegicus