Title : Involvement of an arachidonic-acid-dependent pathway in the interferon-beta-mediated expression of C202 gene in Ehrlich-ascites-tumor cells.

Pub. Date : 1996 Jan 15

PMID : 8631372






3 Functional Relationships(s)
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1 Involvement of an arachidonic-acid-dependent pathway in the interferon-beta-mediated expression of C202 gene in Ehrlich-ascites-tumor cells. Arachidonic Acid interferon beta 1, fibroblast Mus musculus
2 We have shown that treatment of cells with IFN-beta transiently enhances within minutes the release of free arachidonic acid through membrane phospholipase activity. Arachidonic Acid interferon beta 1, fibroblast Mus musculus
3 This suggests that further metabolism of arachidonic acid to epoxides via epoxygenase-catalysed pathways may be a mechanism by which second messengers for IFN-beta-mediated effects on C202 gene expression are generated. Arachidonic Acid interferon beta 1, fibroblast Mus musculus