Title : Oyxsterols induce membrane procoagulant activity in monocytic THP-1 cells.

Pub. Date : 1996 Mar 15

PMID : 8615754






2 Functional Relationships(s)
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1 When THP-1 monocytic cells were cultured in the presence of 7beta-hydroxycholesterol (7beta-OH) or 25-hydroxycholesterol (25-OH), prothrombinase, which reflects anionic phospholipid exposure and tissue factor (TF) procoagulant activities, increased in a time- and dose-dependent manner. 25-hydroxycholesterol coagulation factor III, tissue factor Homo sapiens
2 When THP-1 monocytic cells were cultured in the presence of 7beta-hydroxycholesterol (7beta-OH) or 25-hydroxycholesterol (25-OH), prothrombinase, which reflects anionic phospholipid exposure and tissue factor (TF) procoagulant activities, increased in a time- and dose-dependent manner. 25-hydroxycholesterol coagulation factor III, tissue factor Homo sapiens