Title : A potent new mode of beta-lactamase inhibition revealed by the 1.7 A X-ray crystallographic structure of the TEM-1-BLIP complex.

Pub. Date : 1996 Mar

PMID : 8605632






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The carboxylate of Asp 49 forms hydrogen bonds to four conserved, catalytic residues in the beta-lactamase, thereby mimicking the position of the penicillin G carboxylate observed in the acyl-enzyme complex of TEM-1 with substrate. Hydrogen CD248 molecule Homo sapiens