Title : Regulation of energy metabolism by interleukin-1beta, but not by interleukin-6, is mediated by nitric oxide in primary cultured rat hepatocytes.

Pub. Date : 1996 Mar 27

PMID : 8603098






2 Functional Relationships(s)
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1 Furthermore, interleukin-1beta markedly stimulated nitric oxide formation in hepatocytes, and this increase was blocked by NG-monomethyl-L-arginine (a nitric oxide synthase inhibitor) and by interleukin-1 receptor antagonist. omega-N-Methylarginine interleukin 1 beta Rattus norvegicus
2 NG-monomethyl-L-arginine reversed inhibition of the ATP increase, decrease in the ketone body ratio, and increase in lactate production, which were induced by interleukin-1beta. omega-N-Methylarginine interleukin 1 beta Rattus norvegicus