Pub. Date : 1996 Feb 1
PMID : 8598655
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The purpose of this study was to determine if the inflammatory mediators, endotoxin (LPS) and interferon gamma (IFN), stimulate arginine transport and nitric oxide production in a murine breast cancer cell line. | Arginine | interferon gamma | Mus musculus |
| 2 | Incubation of EMT-6 with LPS and IFN stimulated arginine transport approximately 70% over control levels at 12 hr and transport returned to basal levels at 24 hr. | Arginine | interferon gamma | Mus musculus |
| 3 | Finally, L-arginine was necessary in the media for nitrite accumulation by LPS/IFN-stimulated cells, with maximal accumulation at 1 mM L-arginine. | Arginine | interferon gamma | Mus musculus |
| 4 | Finally, L-arginine was necessary in the media for nitrite accumulation by LPS/IFN-stimulated cells, with maximal accumulation at 1 mM L-arginine. | Arginine | interferon gamma | Mus musculus |
| 5 | In summary, LPS/IFN stimulate arginine transport and NO production in the EMT-6 breast cancer cell line. | Arginine | interferon gamma | Mus musculus |
| 6 | LPS/IFN stimulation of arginine transport may represent an adaptive response to provide increased substrate for enhanced tumor cell NO production. | Arginine | interferon gamma | Mus musculus |