Title : Uncoupling of GTP binding from target stimulation by a single mutation in the transducin alpha subunit.

Pub. Date : 1996 Mar 8

PMID : 8596913






1 Functional Relationships(s)
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Protein Name
Organism
1 Changing the glutamic acid to an alanine in bovine alpha(T) yielded an alpha subunit (alpha(T)E203A) that was fully dependent on rhodopsin for GTP-guanosine diphosphate (GDP) exchange and showed GTP hydrolytic activity similar to that measured for wild-type alpha(T). Guanosine Diphosphate rhodopsin Bos taurus