Title : Osteoclasts and transforming growth factor-beta: estrogen-mediated isoform-specific regulation of production.

Pub. Date : 1996 Feb

PMID : 8593810






2 Functional Relationships(s)
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1 Because both osteoclasts and osteoblasts secrete transforming growth factor-beta (TGF beta), and because 17 beta-estradiol (E2) treatment increases TGF beta production by osteoblast-like cells in vitro, we have investigated the possibility that E2 also may increase the production of TGF beta by isolated osteoclasts in vitro. Estradiol transforming growth factor beta 1 Homo sapiens
2 Because both osteoclasts and osteoblasts secrete transforming growth factor-beta (TGF beta), and because 17 beta-estradiol (E2) treatment increases TGF beta production by osteoblast-like cells in vitro, we have investigated the possibility that E2 also may increase the production of TGF beta by isolated osteoclasts in vitro. Estradiol transforming growth factor beta 1 Homo sapiens