Title : Pharmacological activity of chemically modified subfragment from human serum IgG. XIV. Inhibitory effect of carboxamide-methylated light chain (G1L) on tyrosine phosphorylation and tumor necrosis factor-alpha production from murine macrophages stimulated by lipopolysaccharide.

Pub. Date : 1995 Oct

PMID : 8593440






1 Functional Relationships(s)
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1 Carboxamide-methylated light chain (G1L) from human serum IgG inhibited the secretion of tumor necrosis factor (TNF-alpha), one of the inflammatory cytokines, from adherent splenocytes and thioglycolate-induced peritoneal macrophages. Thioglycolates immunoglobulin heavy chain (V7183 family) Mus musculus