Title : TPA-induced arrest of erythroid differentiation is coupled with downregulation of GATA-1 and upregulation of GATA-2 in an erythroid cell line SAM-1.

Pub. Date : 1996 Feb 1

PMID : 8562972






4 Functional Relationships(s)
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1 TPA-induced arrest of erythroid differentiation is coupled with downregulation of GATA-1 and upregulation of GATA-2 in an erythroid cell line SAM-1. Tetradecanoylphorbol Acetate GATA binding protein 1 Homo sapiens
2 In this report, we performed specific and quantitative measurements of GATA-1 and GATA-2 protein in a new erythroid cell line, SAM-1, after treatment with 12-O-tetradecanoylphorbol 13-acetate (TPA). Tetradecanoylphorbol Acetate GATA binding protein 1 Homo sapiens
3 In this report, we performed specific and quantitative measurements of GATA-1 and GATA-2 protein in a new erythroid cell line, SAM-1, after treatment with 12-O-tetradecanoylphorbol 13-acetate (TPA). Tetradecanoylphorbol Acetate GATA binding protein 1 Homo sapiens
4 On the basis of these measurements, we show that TPA-induced arrest of erythroid differentiation is coupled with the upregulation of GATA-2 protein, as well as the downregulation of GATA-1 protein. Tetradecanoylphorbol Acetate GATA binding protein 1 Homo sapiens